deflate the
trade-offs
The Science Behind the Swelling
Hereditary angioedema is a bradykinin-mediated disease. Innovations focused on this critical element of the HAE attack cascade are essential.1,3
Explore the bradykinin pathway
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WAO Guidelines: Better Control +
Sustained Quality of Life
Managing HAE attack frequency is a necessity. Yet, according to the latest guidelines from the World Allergy Association (WAO), it’s not sufficient. The treat-to-target goal for HAE is now better disease control and sustained improvement in health-related quality of life. Your patients deserve both.3
Read the updated guidelines
HAE, hereditary angioedema.
Review the causes, known triggers, and symptoms of HAE.
Join us in finding a path beyond the burdens of HAE.
REFERENCES
1. Maurer M, Magerl M, Betschel S, et al. The international WAO/EAACI guideline for the management of hereditary angioedema—the 2021 revision and update. Allergy. 2022;77(7):1961-1990.
2. Zuraw BL. The pathophysiology of hereditary angioedema. World Allergy Organ J. 2010;3(9 Suppl):S25-S28.
3. Vázquez DO, Giavina-Bianchi P, Josviack D, et al. The 2025 WAO guidelines for the classification, diagnosis, and treatment of hereditary angioedema, with consideration of worldwide disparities. World Allergy Organ J. 2026;19(5):101335. doi:10.1016/j.waojou.2026.101335